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The Effect of Environmental Chemicals on Insulin Production: Implications for All Types of Diabetes November 15, 2011

Posted by Nancy Hepp in Letters.
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Sarah Howard
Coordinator of CHE’s Diabetes-Obesity Spectrum Working Group

In a recent review, published in the leading diabetes journal Diabetologia, Hectors et al. (2011) describe how numerous environmental chemicals affect the insulin-producing beta cells of the pancreas. These effects, the authors argue, may be significant in the development of type 2 diabetes. Chemicals like bisphenol A, PCBs, dioxin, organophosphorous pesticides, arsenic, heavy metals, and others, can all affect how the beta cells function, and can interfere with their capacity to secrete insulin.

In type 2 diabetes, both insulin resistance—the body’s inability to respond correctly to insulin—and beta cell malfunction contribute to the disease. The inability of the beta cells to produce enough insulin leads to high blood glucose levels, and eventually diabetes (in many people with type 2, insulin production is higher than normal, to compensate for the insulin resistance—but it is still inadequate to bring blood glucose under control).   

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Get a Grip on Toxic Chemicals August 31, 2010

Posted by Nancy Hepp in Letters.
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Reps. Doyle and Murphy are well positioned to help protect us

Maureen Swanson
CHE Partner and Director of the Healthy Children Project for the Learning Disabilities Association of America

This letter was originally published in the Pittsburgh Post-Gazette. It’s republished here with the author’s permission.

Imagine all the chemicals used in televisions, computers, upholstery, car seats, building materials, even children’s pajamas. Imagine that some of these chemicals migrate from products into dust and dirt, and build up in our bodies. They are found in the cord blood of newborns and in breast milk. Imagine that these chemicals are similar in structure to the notorious PCBs – carcinogens banned from use in the late 1970s.

Now wouldn’t you also imagine that these chemicals were tested and found to be safe to human health before they were allowed into our products and homes?

Unfortunately, that is not the case.

Polybrominated diphyenyl ethers are flame retardant chemicals that persist in the environment and build up in the food chain and in people. Laboratory studies link exposure to PBDEs with lowered IQ and attention problems. This summer, a study of pregnant women found that those with higher levels of PBDEs had reduced levels of thyroid hormone, which is essential to a baby’s brain development.

But despite growing scientific evidence linking toxic chemical exposures to serious disease and disability, our government does not require that PBDEs – or any of the other 80,000 chemicals on the market – be tested for effects on human health.

That could be about to change, and two Pittsburgh members of Congress are in key positions to help make it happen.

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Brain Tumour Risk in Relation to Mobile Telephone Use: Results of the INTERPHONE International Case–control Study August 17, 2010

Posted by Nancy Hepp in Letters.
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Stelios A Zinelis
CHE Partner

The Interphone Study Group (2010)1 conducted a study on mobile telephone use has made this conclusion:

“Overall, no increase in risk of glioma or meningioma was observed with the use of mobile phones. There were suggestions of an increased risk of glioma at the highest exposure levels, but biases and errors prevent a causal interpretation.”

This study was completed in 2004, but for unknown reasons, the results were  published six years later, upon demand by scientific organisations such as the European Environment Agency and the European Union (2009)2 (which partially funded the study, along with the International Union against Cancer [Mobile Manufacturers Forum and GSM Association]),  who were concerned about the effects of mobile phone use on public health.

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